MATERNAL LIPID PROFILE AND IT’S ADVERSE OUTCOMES IN PREGNANCY

Abstract

Introduction: Pregnancy-induced lipid changes support fetal growth but dyslipidemia may increase risks of gestational diabetes, preeclampsia, intrauterine growth restriction, macrosomia, and preterm birth. Aims: To assess maternal lipid profiles at 24–36 weeks and their association with adverse pregnancy outcomes. Results: Among 250 women (mean age 27.4 ± 4.6 years), dyslipidemia occurred in 36%. Elevated triglycerides (≥195 mg/dL), LDL C (≥132 mg/dL), and low HDL-C (<41 mg/dL) were linked to higher rates of GDM (17% vs 6%, p<0.001), preeclampsia (12% vs 5%, p<0.001), preterm birth (12% vs 6%, p=0.001), and macrosomia (10% vs 6%, p=0.003). Multivariate analysis showed elevated TG (OR 2.5), high LDL-C (OR 2.1), and low HDL-C (OR 1.9) independently predicted complications. Conclusion: Routine lipid screening during pregnancy can identify at-risk women, enabling timely interventions.